Yeah there was one minor side thing I did last night that blew me away (spoilers):
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The TV host who's son had been kidnapped and murdered. It was recorded by the gang, and I had to infiltrate and take back the raw, unedited video of his murder from the two guys who had edited it. Started off as a typical base invasion thing, scattered with tidbits of info and conversation that built it as a whole and then to confront them only to realise that they gave no fucks, what they viewed and cut (paedophilia, bestiality, murder) and their complete apathy towards it gave me such a visceral reaction. I shot the father mid-conversation and saw the son display emotion I didn't think he held within him. I then shot the son. And it actually felt justified rather than just shooting for the sake of it.
Had some actual heft to it, and it was a tiny little bit of the game. Gave me a reaction akin to that famous scene in Spec Ops: The Line.